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Bis[3,5-bis(benzylidene)-4-oxo-1-piperidinyl]amides: A Novel Class of Potent Cytotoxins

The principal objective of this study was the examination of the theory of cytotoxic synergism. In this exploratory study, we tested the hypothesis that doubling the number of sites available for thiol alkylation in a series of candidate cytotoxins increases potency more than two-fold. This concept...

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書誌詳細
主要な著者: Das, Swagatika, Das, Umashankar, Varela-Ramírez, Armando, Lema, Carolina, Aguilera, Renato J., Balzarini, Jan, De Clercq, Erik, Dimmock, Stephen G., Gorecki, Dennis K. J., Dimmock, Jonathan R.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344817/
https://ncbi.nlm.nih.gov/pubmed/21826795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201100199
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