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Inactive O6-methylguanine-DNA methyltransferase in human cells.
A plasmid encoding a recombinant human O6-methylguanine-DNA methyltransferase (MGMT) fused to a fragment of the bacteriophage lambda N protein has been constructed. The fusion protein retained methyltransferase activity when expressed at high levels in E.coli and was purified to essential homogeneit...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
1992
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC334476/ https://ncbi.nlm.nih.gov/pubmed/1461738 |
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