A carregar...

Selective and cell-active inhibitors of the USP1/UAF1 deubiquitinase complex reverse cisplatin resistance in non-small cell lung cancer cells

Ubiquitin-specific proteases (USPs) have in recent years emerged as a promising therapeutic target class. We identified selective small-molecule inhibitors against a deubiquitinase complex, the human USP1/UAF1, through quantitative high throughput screening (qHTS) of a collection of bioactive molecu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chen, Junjun, Dexheimer, Thomas S., Ai, Yongxing, Liang, Qin, Villamil, Mark A., Inglese, James, Maloney, David J, Jadhav, Ajit, Simeonov, Anton, Zhuang, Zhihao
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344384/
https://ncbi.nlm.nih.gov/pubmed/22118673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.08.014
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!