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Purification and characterization of NF-R1 that regulates the expression of the human multidrug resistance (MDR1) gene.
We have purified a protein, NF-R1, that specifically binds to two unrelated motifs--the ATTCAGTCA motif and the GC-box motif--on the MDR1 proximal promoter. Purified NF-R1 has been confirmed by southwestern blotting to be a 110-kDa protein. Methylation interference analysis revealed that the nucleot...
Kaydedildi:
| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
1992
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| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC334420/ https://ncbi.nlm.nih.gov/pubmed/1360648 |
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