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Purification and Characterization of NF‐R2 that Regulates the Expression of the Human Multidrug Resistance (MDR1) Gene

NF‐R2 is a DNA‐binding protein that interacts with the MDR1 gene proximal promoter sequence. We previously reported that NF‐R2 binds within the promoter's — 126 and — 102 regions, which contain the ATTCAGTCA motif. In the present study, we have purified NF‐R2 from the nuclear extract of K562/AD...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Principais autores: Takatori, Toshiro, Ogura, Mitsuo, Tsuruo, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919146/
https://ncbi.nlm.nih.gov/pubmed/8098026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1993.tb02870.x
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