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Trans-dominant inhibition of transcription activator LFB1.

Liver-enriched factor LFB1 (also named HNF1) is a dimeric transcription activator which is essential for the expression of many hepatocyte-specific genes. Here we demonstrate that LFB1 mutants in the POU A-like or in the homeo domains inhibit wild-type DNA binding by forming inactive heterodimeric c...

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Hlavní autoři: Nicosia, A, Tafi, R, Monaci, P
Médium: Artigo
Jazyk:Inglês
Vydáno: 1992
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC334337/
https://ncbi.nlm.nih.gov/pubmed/1331985
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