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Synergistic trans-activation of the human C-reactive protein promoter by transcription factor HNF-1 binding at two distinct sites.

The promoter region of the human C-reactive protein (CRP) gene comprises two distinct regions (APREs, for Acute Phase Responsive Elements) each one containing information necessary and sufficient for liver specific and IL-6 inducible expression in human hepatoma Hep3B cells. In this paper we show th...

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Main Authors: Toniatti, C, Demartis, A, Monaci, P, Nicosia, A, Ciliberto, G
格式: Artigo
語言:Inglês
出版: 1990
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC552239/
https://ncbi.nlm.nih.gov/pubmed/2265613
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