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Organismal propagation in the absence of a functional telomerase pathway in Caenorhabditis elegans

To counteract replication-dependent telomere shortening most eukaryotic cells rely on the telomerase pathway, which is crucial for the maintenance of proliferative potential of germ and stem cell populations of multicellular organisms. Likewise, cancer cells usually engage the telomerase pathway for...

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Autori principali: Lackner, Daniel H, Raices, Marcela, Maruyama, Hugo, Haggblom, Candy, Karlseder, Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343340/
https://ncbi.nlm.nih.gov/pubmed/22425786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.61
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