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C. elegans survivors without telomerase

In most eukaryotic organisms with a linear genome, the telomerase complex is essential for telomere maintenance and, thus, for genomic integrity. Proper telomerase function in stem and germ cell populations counteracts replication-dependent telomere shortening. On the other hand, repression of telom...

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Bibliographic Details
Main Authors: Lackner, Daniel H., Karlseder, Jan
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670455/
https://ncbi.nlm.nih.gov/pubmed/24058854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/worm.21073
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