Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC

Autophagy is a catabolic process by which cytoplasmic components are sequestered and transported by autophagosomes to lysosomes for degradation, enabling recycling of these components and providing cells with amino acids during starvation. It is a highly regulated process and its deregulation contri...

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Hlavní autoři: McKnight, Nicole C, Jefferies, Harold B J, Alemu, Endalkachew A, Saunders, Rebecca E, Howell, Michael, Johansen, Terje, Tooze, Sharon A
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343327/
https://ncbi.nlm.nih.gov/pubmed/22354037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.36
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