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Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity
Autophagy is a highly conserved degradative pathway, essential for cellular homeostasis and implicated in diseases including cancer and neurodegeneration. Autophagy-related 8 (ATG8) proteins play a central role in autophagosome formation and selective delivery of cytoplasmic cargo to lysosomes by re...
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| Publicado no: | J Mol Biol |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8202330/ https://ncbi.nlm.nih.gov/pubmed/33845085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2021.166987 |
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