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Mechanism for nucleic acid chaperone activity of HIV-1 nucleocapsid protein revealed by single molecule stretching

The nucleocapsid protein (NC) of HIV type 1 is a nucleic acid chaperone that facilitates the rearrangement of nucleic acids into conformations containing the maximum number of complementary base pairs. We use an optical tweezers instrument to stretch single DNA molecules from the helix to coil state...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Williams, Mark C., Rouzina, Ioulia, Wenner, Jay R., Gorelick, Robert J., Musier-Forsyth, Karin, Bloomfield, Victor A.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC33432/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11344257/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.101033198
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