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Stemness of the Organ of Corti Relates to the Epigenetic Status of Sox2 Enhancers

In the adult mammalian auditory epithelium, the organ of Corti, loss of sensory hair cells results in permanent hearing loss. The underlying cause for the lack of regenerative response is the depletion of otic progenitors in the cell pool of the sensory epithelium. Here, we show that an increase in...

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Detalhes bibliográficos
Main Authors: Waldhaus, Jörg, Cimerman, Jelka, Gohlke, Henning, Ehrich, Mathias, Müller, Marcus, Löwenheim, Hubert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343037/
https://ncbi.nlm.nih.gov/pubmed/22570694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036066
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