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Stemness of the Organ of Corti Relates to the Epigenetic Status of Sox2 Enhancers
In the adult mammalian auditory epithelium, the organ of Corti, loss of sensory hair cells results in permanent hearing loss. The underlying cause for the lack of regenerative response is the depletion of otic progenitors in the cell pool of the sensory epithelium. Here, we show that an increase in...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3343037/ https://ncbi.nlm.nih.gov/pubmed/22570694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036066 |
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