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Normalization, bias correction, and peak calling for ChIP-seq

Next-generation sequencing is rapidly transforming our ability to profile the transcriptional, genetic, and epigenetic states of a cell. In particular, sequencing DNA from the immunoprecipitation of protein-DNA complexes (ChIP-seq) and methylated DNA (MeDIP-seq) can reveal the locations of protein b...

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Bibliografske podrobnosti
Main Authors: Diaz, Aaron, Park, Kiyoub, Lim, Daniel A., Song, Jun S.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342857/
https://ncbi.nlm.nih.gov/pubmed/22499706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/1544-6115.1750
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