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A Generalized Linear Model for Peak Calling in ChIP-Seq Data

Chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-Seq) has become a routine for detecting genome-wide protein-DNA interaction. The success of ChIP-Seq data analysis highly depends on the quality of peak calling (i.e., to detect peaks of tag counts at a genomic location an...

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Bibliographic Details
Main Authors: Xu, Jialin, Zhang, Yu
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375645/
https://ncbi.nlm.nih.gov/pubmed/22533622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2012.0023
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