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Inhibition of hsp90 attenuates pro-inflammatory cytokines and prevents LPS induced liver injury
BACKGROUND: Endotoxin mediated pro-inflammatory cytokines play a significant role in pathogenesis of acute and chronic liver diseases. Hsp90 functions as an important chaperone of LPS signaling and is required for production of pro-inflammatory cytokines. We hypothesized that inhibition of hsp90 pre...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3342823/ https://ncbi.nlm.nih.gov/pubmed/22105779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24802 |
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