Serum osteoprotegerin is increased and predicts survival in idiopathic pulmonary arterial hypertension

We previously reported that osteoprotegerin (OPG) is regulated by pathways associated with pulmonary arterial hypertension (PAH), and is present at elevated levels within pulmonary vascular lesions and sera from patients with idiopathic PAH (IPAH). Since OPG is a naturally secreted protein, we inves...

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Detalhes bibliográficos
Main Authors: Condliffe, Robin, Pickworth, Josephine A., Hopkinson, Kay, Walker, Sara J., Hameed, Abdul G., Suntharaligam, Jay, Soon, Elaine, Treacy, Carmen, Pepke-Zaba, Joanna, Francis, Sheila E., Crossman, David C., Newman, Christopher M. H., Elliot, Charles A., Morton, Allison C., Morrell, Nicholas W., Kiely, David G., Lawrie, Allan
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342744/
https://ncbi.nlm.nih.gov/pubmed/22558516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2045-8932.94819
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