Chargement en cours...
Point mutations in a nucleoside transporter gene from Leishmania donovani confer drug resistance and alter substrate selectivity
Leishmania parasites lack a purine biosynthetic pathway and depend on surface nucleoside and nucleobase transporters to provide them with host purines. Leishmania donovani possess two closely related genes that encode high affinity adenosine-pyrimidine nucleoside transporters LdNT1.1 and LdNT1.2 and...
Enregistré dans:
| Auteurs principaux: | , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The National Academy of Sciences
2001
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC33427/ https://ncbi.nlm.nih.gov/pubmed/11353834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.101537298 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|