Llwytho...
Point mutations in a nucleoside transporter gene from Leishmania donovani confer drug resistance and alter substrate selectivity
Leishmania parasites lack a purine biosynthetic pathway and depend on surface nucleoside and nucleobase transporters to provide them with host purines. Leishmania donovani possess two closely related genes that encode high affinity adenosine-pyrimidine nucleoside transporters LdNT1.1 and LdNT1.2 and...
Wedi'i Gadw mewn:
| Prif Awduron: | , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
The National Academy of Sciences
2001
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC33427/ https://ncbi.nlm.nih.gov/pubmed/11353834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.101537298 |
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