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Signaling thresholds govern heterogeneity in IL-7-receptor-mediated responses of naïve CD8(+) T cells
Variable sensitivity to T-cell-receptor (TCR)- and IL-7-receptor (IL-7R)-mediated homeostatic signals among naïve T cells has thus far been largely attributed to differences in TCR specificity. We show here that even when withdrawn from self-peptide-induced TCR stimulation, CD8(+) T cells exhibit he...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3342499/ https://ncbi.nlm.nih.gov/pubmed/21339767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2011.5 |
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