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Enhancer and promoter interactions — long distance calls

In metazoans, enhancers of gene transcription must often exert their effects over tens of kilobases of DNA. Over the last decade it has become clear that to do this, enhancers come into close proximity with target promoters with the looping away of intervening sequences. In a few cases proteins that...

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Detalhes bibliográficos
Main Authors: Krivega, Ivan, Dean, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342482/
https://ncbi.nlm.nih.gov/pubmed/22169023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2011.11.001
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