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Boundaries mediate long-distance interactions between enhancers and promoters in the Drosophila Bithorax complex

Drosophila bithorax complex (BX-C) is one of the best model systems for studying the role of boundaries (insulators) in gene regulation. Expression of three homeotic genes, Ubx, abd-A, and Abd-B, is orchestrated by nine parasegment-specific regulatory domains. These domains are flanked by boundary e...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Postika, Nikolay, Metzler, Mario, Affolter, Markus, Müller, Martin, Schedl, Paul, Georgiev, Pavel, Kyrchanova, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306242/
https://ncbi.nlm.nih.gov/pubmed/30540750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007702
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