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Definition of NOTCH3 target genes in ovarian cancer

NOTCH3 gene amplification plays an important role in the progression of many ovarian and breast cancers, but the targets of NOTCH3 signaling are unclear. Here we report the use of an integrated systems biology approach to identify direct target genes for NOTCH3. Transcriptome analysis showed that su...

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Hlavní autoři: Chen, Xu, Thiaville, Michelle M., Chen, Li, Stoeck, Alexander, Xuan, Jason, Gao, Min, Shih, Ie-Ming, Wang, Tian-Li
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342447/
https://ncbi.nlm.nih.gov/pubmed/22396495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2181
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