Identification of PBX1 Target Genes in Cancer Cells by Global Mapping of PBX1 Binding Sites

PBX1 is a TALE homeodomain transcription factor involved in organogenesis and tumorigenesis. Although it has been shown that ovarian, breast, and melanoma cancer cells depend on PBX1 for cell growth and survival, the molecular mechanism of how PBX1 promotes tumorigenesis remains unclear. Here, we ap...

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Detalhes bibliográficos
Main Authors: Thiaville, Michelle M., Stoeck, Alexander, Chen, Li, Wu, Ren-Chin, Magnani, Luca, Oidtman, Jessica, Shih, Ie-Ming, Lupien, Mathieu, Wang, Tian-Li
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342315/
https://ncbi.nlm.nih.gov/pubmed/22567123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036054
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