Identification of PBX1 Target Genes in Cancer Cells by Global Mapping of PBX1 Binding Sites

PBX1 is a TALE homeodomain transcription factor involved in organogenesis and tumorigenesis. Although it has been shown that ovarian, breast, and melanoma cancer cells depend on PBX1 for cell growth and survival, the molecular mechanism of how PBX1 promotes tumorigenesis remains unclear. Here, we ap...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Thiaville, Michelle M., Stoeck, Alexander, Chen, Li, Wu, Ren-Chin, Magnani, Luca, Oidtman, Jessica, Shih, Ie-Ming, Lupien, Mathieu, Wang, Tian-Li
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342315/
https://ncbi.nlm.nih.gov/pubmed/22567123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036054
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