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Definition of NOTCH3 target genes in ovarian cancer

NOTCH3 gene amplification plays an important role in the progression of many ovarian and breast cancers, but the targets of NOTCH3 signaling are unclear. Here we report the use of an integrated systems biology approach to identify direct target genes for NOTCH3. Transcriptome analysis showed that su...

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Detalhes bibliográficos
Main Authors: Chen, Xu, Thiaville, Michelle M., Chen, Li, Stoeck, Alexander, Xuan, Jason, Gao, Min, Shih, Ie-Ming, Wang, Tian-Li
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342447/
https://ncbi.nlm.nih.gov/pubmed/22396495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2181
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