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Activation and repression sequences determine the lens-specific expression of the rat gamma D-crystallin gene.
Rat lens nuclear extracts contain a factor that binds to position -57 to -46 of the rat gamma D-crystallin promoter region. This factor protects the sequence 5'-CTGCCAACGCAG-3' in a footprint analysis. Binding to this region is crucial for maximal promoter activity in rat lens cells, but t...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1992
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC334244/ https://ncbi.nlm.nih.gov/pubmed/1408802 |
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