Activation and repression sequences determine the lens-specific expression of the rat gamma D-crystallin gene.
Rat lens nuclear extracts contain a factor that binds to position -57 to -46 of the rat gamma D-crystallin promoter region. This factor protects the sequence 5'-CTGCCAACGCAG-3' in a footprint analysis. Binding to this region is crucial for maximal promoter activity in rat lens cells, but this sequen...
Gardado en:
| Publicado en: | Nucleic Acids Res |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
1992
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| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334244/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1408802/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.18.4865 |
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