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Lability of monofunctional cis-platinum adducts: role of DNA double helix.
Recently, we have shown that the adduct formed in the reaction between the platinum-triamine complex cis-[Pt(NH3)2(N7-N-methyl-2-diazapyrenium)Cl]2+ and one single-stranded oligonucleotide was stable but became labile as soon as the platinated oligonucleotide was paired with its complementary strand...
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| Główni autorzy: | , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
1992
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| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC334238/ https://ncbi.nlm.nih.gov/pubmed/1408797 |
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