Lability of monofunctional cis-platinum adducts: role of DNA double helix.
Recently, we have shown that the adduct formed in the reaction between the platinum-triamine complex cis-[Pt(NH3)2(N7-N-methyl-2-diazapyrenium)Cl]2+ and one single-stranded oligonucleotide was stable but became labile as soon as the platinated oligonucleotide was paired with its complementary strand...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1992
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334238/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1408797/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.18.4825 |
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