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Lability of monofunctional cis-platinum adducts: role of DNA double helix.

Recently, we have shown that the adduct formed in the reaction between the platinum-triamine complex cis-[Pt(NH3)2(N7-N-methyl-2-diazapyrenium)Cl]2+ and one single-stranded oligonucleotide was stable but became labile as soon as the platinated oligonucleotide was paired with its complementary strand...

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Sonraí Bibleagrafaíochta
Main Authors: Anin, M F, Gaucheron, F, Leng, M
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1992
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC334238/
https://ncbi.nlm.nih.gov/pubmed/1408797
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