TCR Mechanobiology: Torques and Tunable Structures Linked to Early T Cell Signaling

Mechanotransduction is a basis for receptor signaling in many biological systems. Recent data based upon optical tweezer experiments suggest that the TCR is an anisotropic mechanosensor, converting mechanical energy into biochemical signals upon specific peptide-MHC complex (pMHC) ligation. Tangenti...

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Bibliografiska uppgifter
Huvudupphovsmän: Kim, Sun Taek, Shin, Yongdae, Brazin, Kristine, Mallis, Robert J., Sun, Zhen-Yu J., Wagner, Gerhard, Lang, Matthew J., Reinherz, Ellis L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Research Foundation 2012
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342345/
https://ncbi.nlm.nih.gov/pubmed/22566957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00076
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