TCR Mechanobiology: Torques and Tunable Structures Linked to Early T Cell Signaling

Mechanotransduction is a basis for receptor signaling in many biological systems. Recent data based upon optical tweezer experiments suggest that the TCR is an anisotropic mechanosensor, converting mechanical energy into biochemical signals upon specific peptide-MHC complex (pMHC) ligation. Tangenti...

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Detalhes bibliográficos
Main Authors: Kim, Sun Taek, Shin, Yongdae, Brazin, Kristine, Mallis, Robert J., Sun, Zhen-Yu J., Wagner, Gerhard, Lang, Matthew J., Reinherz, Ellis L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342345/
https://ncbi.nlm.nih.gov/pubmed/22566957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00076
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