In vivo efficacy of the histone deacetylase inhibitor suberoylanilide hydroxamic acid in combination with radiotherapy in a malignant rhabdoid tumor mouse model

PURPOSE: Histone deacetylase inhibitors are promising new substances in cancer therapy and have also been shown to sensitize different tumor cells to irradiation (XRT). We explored the effect as well as the radiosensitizing properties of suberoylanilide hydroxamic acid (SAHA) in vivo in a malignant...

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Hlavní autoři: Thiemann, Markus, Oertel, Susanne, Ehemann, Volker, Weichert, Wilko, Stenzinger, Albrecht, Bischof, Marc, Weber, Klaus-J, Perez, Ramon Lopez, Haberkorn, Uwe, Kulozik, Andreas E, Debus, Jürgen, Huber, Peter E, Battmann, Claudia
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342162/
https://ncbi.nlm.nih.gov/pubmed/22458853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-7-52
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