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Insights into T Cell Recognition of Antigen: Significance of Two-Dimensional Kinetic Parameters
The T cell receptor (TCR) interacts with peptide-major histocompatibility complex (pMHC) to enable T cell development and trigger adaptive immune responses. For this reason, TCR:pMHC interactions have been intensely studied for over two decades. However, the details of how various binding parameters...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Frontiers Research Foundation
2012
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3342060/ https://ncbi.nlm.nih.gov/pubmed/22566966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00086 |
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