Solution structure of DFF40 and DFF45 N-terminal domain complex and mutual chaperone activity of DFF40 and DFF45

Apoptotic DNA fragmentation is mediated by a caspase-activated DNA fragmentation factor (DFF)40. Expression and folding of DFF40 require the presence of DFF45, which also acts as a nuclease inhibitor before DFF40 activation by execution caspases. The N-terminal domains (NTDs) of both proteins are ho...

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Hlavní autoři: Zhou, Pei, Lugovskoy, Alexey A., McCarty, John S., Li, Peng, Wagner, Gerhard
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2001
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC33420/
https://ncbi.nlm.nih.gov/pubmed/11371636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.111145098
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