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Corepressor-induced organization and assembly of the biotin repressor: A model for allosteric activation of a transcriptional regulator
The Escherichia coli biotin repressor binds to the biotin operator to repress transcription of the biotin biosynthetic operon. In this work, a structure determined by x-ray crystallography of a complex of the repressor bound to biotin, which also functions as an activator of DNA binding by the bioti...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC33419/ https://ncbi.nlm.nih.gov/pubmed/11353844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.111128198 |
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