Wordt geladen...

SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway

AIMS: Impaired myocardial sarcoplasmic reticulum calcium ATPase 2a (SERCA2a) activity is a hallmark of failing hearts, and SERCA2a gene therapy improves cardiac function in animals and patients with heart failure (HF). Deregulation of microRNAs has been demonstrated in HF pathophysiology. We studied...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Kumarswamy, Regalla, Lyon, Alexander R., Volkmann, Ingo, Mills, Adam M., Bretthauer, Julia, Pahuja, Aanchal, Geers-Knörr, Cornelia, Kraft, Theresia, Hajjar, Roger J., Macleod, Kenneth T., Harding, Sian E., Thum, Thomas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341631/
https://ncbi.nlm.nih.gov/pubmed/22362515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehs043
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!