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SERCA2a gene therapy in heart failure: an anti-arrhythmic positive inotrope

Therapeutic options that directly enhance cardiomyocyte contractility in chronic heart failure (HF) therapy are currently limited and do not improve prognosis. In fact, most positive inotropic agents, such as β-adrenoreceptor agonists and PDE inhibitors, which have been assessed in HF patients, caus...

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Detalhes bibliográficos
Main Authors: Sikkel, Markus B, Hayward, Carl, MacLeod, Kenneth T, Harding, Sian E, Lyon, Alexander R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874695/
https://ncbi.nlm.nih.gov/pubmed/24138023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12472
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