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Computational Analysis of the Regulation of EGFR by Protein Tyrosine Phosphatases

The tyrosine phosphorylated epidermal growth factor receptor (EGFR) initiates numerous cell signaling pathways. Although EGFR phosphorylation levels are ultimately determined by the balance of receptor kinase and protein tyrosine phosphatase (PTP) activities, the kinetics of EGFR dephosphorylation a...

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Autors principals: Monast, Calixte S., Furcht, Christopher M., Lazzara, Matthew J.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341563/
https://ncbi.nlm.nih.gov/pubmed/22824264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.03.037
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