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Computational Analysis of the Regulation of EGFR by Protein Tyrosine Phosphatases

The tyrosine phosphorylated epidermal growth factor receptor (EGFR) initiates numerous cell signaling pathways. Although EGFR phosphorylation levels are ultimately determined by the balance of receptor kinase and protein tyrosine phosphatase (PTP) activities, the kinetics of EGFR dephosphorylation a...

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Detalhes bibliográficos
Main Authors: Monast, Calixte S., Furcht, Christopher M., Lazzara, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341563/
https://ncbi.nlm.nih.gov/pubmed/22824264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.03.037
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