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Probing Tubulin-Blocked State of VDAC by Varying Membrane Surface Charge
Reversible blockage of the voltage-dependent anion channel (VDAC) of the mitochondrial outer membrane by dimeric tubulin is being recognized as a potent regulator of mitochondrial respiration. The tubulin-blocked state of VDAC is impermeant for ATP but only partially closed for small ions. This resi...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3341544/ https://ncbi.nlm.nih.gov/pubmed/22824270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.03.058 |
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