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In Vivo Phosphorylation Site Mapping in Mouse Cardiac Troponin I by High Resolution Top-Down Electron Capture Dissociation Mass Spectrometry: Ser22/23 Are the Only Sites Basally Phosphorylated

Cardiac troponin I (cTnI) is the inhibitory subunit of cardiac troponin, a key myofilament regulatory protein complex located on the thin filaments of the contractile apparatus. cTnI is uniquely specific for the heart and is widely used in clinics as a serum biomarker for cardiac injury. Phosphoryla...

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Detalhes bibliográficos
Main Authors: Ayaz-Guner, Serife, Zhang, Jiang, Li, Lin, Walker, Jeffery W., Ge, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341416/
https://ncbi.nlm.nih.gov/pubmed/19637843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900739f
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