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Bleomycin mediated degradation of DNA-RNA hybrids does not involve C-1' chemistry.

Incubation of Fe(II) bleomycin and O2 with a number of 'A'-like DNA-RNA hybrid homopolymers at 4 atm O2 results in formation of base propenal and base in a ratio of approximately 1.0:1.0. This ratio differs dramatically from the corresponding ratio of approximately 10:1.0 observed when act...

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Bibliographische Detailangaben
Hauptverfasser: Absalon, M J, Krishnamoorthy, C R, McGall, G, Kozarich, J W, Stubbe, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC334123/
https://ncbi.nlm.nih.gov/pubmed/1380696
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