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Contributions of NMR to the Understanding of the Coordination Chemistry and DNA Interactions of Metallo-Bleomycins

Bleomycins are a family of glycopeptide antibiotics that have the ability to bind and degrade DNA when bound to key metal ions, which is believed to be responsible for their antitumor activity. Knowledge of the structures of metallo-bleomycins is vital to further characterize their mechanism of acti...

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Bibliografski detalji
Izdano u:Molecules
Glavni autori: Lehmann, Teresa, Topchiy, Elena
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270211/
https://ncbi.nlm.nih.gov/pubmed/23917114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18089253
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