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Degradation of DNA RNA Hybrids by Ribonuclease H and DNA Polymerases of Cellular and Viral Origin

Ribonuclease H from human KB cells, chick embryos, calf thymus, avian myeloblastosis virus, and Rous associated virus specifically degrades the RNA of DNA·RNA hybrids, producing mono- and oligoribonucleotides terminated in 5′-phosphates. The cellular RNase H is an endonuclease, whereas the viral enz...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Keller, Walter, Crouch, Robert
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1972
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389771/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4343966/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.11.3360
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