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Chk1 suppresses bypass of mitosis and tetraploidization in p53-deficient cancer cells
Many cancer cells are unable to maintain a numerically stable chromosome complement. It is well established that aberrant cell division can generate progeny with increased ploidy, but the genetic factors required for maintenance of diploidy are not well understood. Using an isogenic model system der...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Landes Bioscience
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3341228/ https://ncbi.nlm.nih.gov/pubmed/22433954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.19944 |
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