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Agonist-induced conformational changes in the G-protein-coupling domain of the β(2) adrenergic receptor
The majority of extracellular physiologic signaling molecules act by stimulating GTP-binding protein (G-protein)-coupled receptors (GPCRs). To monitor directly the formation of the active state of a prototypical GPCR, we devised a method to site specifically attach fluorescein to an endogenous cyste...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The National Academy of Sciences
2001
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC33412/ https://ncbi.nlm.nih.gov/pubmed/11353823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.101126198 |
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