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Targeted cancer therapy: giving histone deacetylase inhibitors all they need to succeed
Histone deacetylase inhibitors (HDACis) have now emerged as a powerful new class of small-molecule therapeutics acting through the regulation of the acetylation states of histone proteins (a form of epigenetic modulation) and other non-histone protein targets. Over 490 clinical trials have been init...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3341130/ https://ncbi.nlm.nih.gov/pubmed/22416777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.12.3 |
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