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Selectively Targeting Prostate Cancer with Antiandrogen Equipped Histone Deacetylase Inhibitors

Diverse cellular processes relevant to cancer progression are regulated by the acetylation status of proteins. Among such processes is chromatin remodeling via histone proteins, controlled by opposing histone deacetylase (HDAC) and histone acetyltransferase (HAT) enzymes. Histone deacetylase inhibit...

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Detalhes bibliográficos
Main Authors: Gryder, Berkley E., Akbashev, Michelle J., Rood, Michael K., Raftery, Eric D., Meyers, Warren M., Dillard, Paulette, Khan, Shafiq, Oyelere, Adegboyega K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836611/
https://ncbi.nlm.nih.gov/pubmed/24004176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400542w
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