Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity

The majority of human breast cancers exhibit luminal epithelial differentiation. However, most aggressive behavior, including invasion and purported cancer stem cell activity, are considered characteristics of basal-like cells. We asked the following questions: Must luminal-like breast cancer cells...

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Autors principals: Kim, Jiyoung, Villadsen, René, Sørlie, Therese, Fogh, Louise, Grønlund, Signe Z., Fridriksdottir, Agla J., Kuhn, Irene, Rank, Fritz, Wielenga, Vera Timmermans, Solvang, Hiroko, Edwards, Paul A. W., Børresen-Dale, Anne-Lise, Rønnov-Jessen, Lone, Bissell, Mina J., Petersen, Ole William
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341000/
https://ncbi.nlm.nih.gov/pubmed/22454501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203203109
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